In this few weeks, I have been hearing more and more of Ajax and Ajax wrapper variants. Of course as a .NET developer, I will stick to Ajax.NET wrapper. Today, I learn a new wrapper SAJAX Toolkit. S for Simple.
URL @ http://absinth.modernmethod.com/sajax/

Basically an Ajax wrapper for PHP / ASP / Coldfusion developers.

but there is also CFAJAX for Coldfusion, and there is also Backbase
With so many choice to choose from, its not difficult to see Ajax is gaining popularity. But whether it will change how web sites looks like in the future is yet to be seen